Blar i Brage NIH på forfatter "Baehr, Leslie M."
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Knockdown of the E3 Ubiquitin ligase UBR5 and its role in skeletal muscle anabolism
Hughes, David C.; Turner, Daniel C.; Baehr, Leslie M.; Seaborne, Robert A.; Viggars, Mark; Jarvis, Jonathan C.; Gorski, Piotr Patryk; Stewart, Claire E.; Owens, Daniel J.; Bodine, Sue C.; Sharples, Adam (Peer reviewed; Journal article, 2020)UBR5 is an E3-ubiquitin-ligase positively associated with anabolism, hypertrophy and recovery from atrophy in skeletal muscle. The precise mechanisms underpinning UBR5's role in the regulation of skeletal muscle mass remains ... -
Ubiquitin ligases in longevity and aging skeletal muscle
Hughes, David C.; Baehr, Leslie M.; Waddell, David S.; Sharples, Adam; Bodine, Sue C. (Peer reviewed; Journal article, 2022)The development and prevalence of diseases associated with aging presents a global health burden on society. One hallmark of aging is the loss of proteostasis which is caused in part by alterations to the ubiquitin–proteasome ...